Insider txns (12m)
100
Stock / equity
PRAX Praxis Precision Medicines, Inc.
- Security
- Equity
- Size, estimated from filings
- Mid cap ($2B – $10B)
- Insiders on record
- 14
- Members of Congress
- 1
- Latest trade on record
- September 29, 2026
PRAX (Praxis Precision Medicines, Inc.) has 100 disclosed insider transactions from 13 insiders in the last 12 months (0 open-market buys, 31 sales, about $18.0M at reported prices) and 2 congressional trades from 1 member of Congress. The most recent disclosure was filed October 12, 2026.
Open-market buys / sales
0 / 31
Congress trades (12m)
2
Distinct filers (12m)
14
Share price
Price and chart by TradingView for Praxis Precision Medicines, Inc.. US share prices here are delayed, not real-time. The trade records on this page come from government filings, not from this chart.
PRAX in charts
Who is trading this stock
Which people account for the buying and selling over the last 12 months?
BoughtSold
7 people account for the disclosed buying and selling in PRAX over the last 12 months; the most active is Nemiroff Alex with $5.4M.
Prices insiders traded at
What price did insiders buy and sell at? Each marker is one open-market trade at the share price reported on its Form 4.
▲ Bought▼ SoldAverage reported price that day
Insiders reported 28 open-market trades in PRAX since Oct 16, 2025, at prices from $90.00 to $316; the most recent was a sale at $301 on Jun 24, 2026. These are the prices on the filings, not adjusted for stock splits, and not a market price series.
Insider holdings over time
Is an insider building or unwinding a position? Shares held directly after each filing.
Souza MarcioMastrocola Lauren
Souza Marcio reported 0 shares held after the latest filing, against 2,600 at the first on record.
Lobbying spend by quarter
How much has Praxis Precision Medicines, Inc. reported spending on federal lobbying?
Praxis Precision Medicines, Inc. reported $320K in lobbying over the last eight quarters, from filings matched by exact company name.
Insiders trading PRAX
Everyone who filed a Form 4 for this ticker, by number of rows on record. "Bought" and "sold" count open-market purchases (code P) and sales only; awards, option exercises and shares withheld for tax are in the row count but not in those two columns.
| Insider | Role | Rows | Bought | Sold | Value bought | Value sold | Latest |
|---|---|---|---|---|---|---|---|
| Mastrocola Lauren | Principal Accounting Officer | 22 | 0 | 5 | — | $2.8M | May 14, 2026 |
| Nemiroff Alex | General Counsel and Secretary | 20 | 0 | 7 | — | $5.4M | May 14, 2026 |
| DeSimone Jill | Director | 18 | 0 | 12 | — | $3.6M | June 24, 2026 |
| Adage Capital Management, L.P. | Insider | 10 | 0 | 10 | — | $33.2M | October 16, 2025 |
| Souza Marcio | Chief Executive Officer | 8 | 0 | 2 | — | $1.3M | July 8, 2026 |
| Kelly Timothy Edwin | Chief Financial Officer | 7 | 0 | 3 | — | $686K | May 14, 2026 |
| Arbuckle Stuart A | Director | 5 | 0 | 0 | — | — | June 10, 2026 |
| KINDLER JEFFREY B | Director | 5 | 0 | 0 | — | — | June 10, 2026 |
| Sniecinski Megan | Chief Operating Officer | 5 | 0 | 2 | — | $558K | May 14, 2026 |
| Chodakewitz Jeffrey | Director | 2 | 0 | 0 | — | — | June 10, 2026 |
| Cudkowicz Merit Ester | Director | 2 | 0 | 0 | — | — | June 10, 2026 |
| MITCHELL DEAN J | Director | 2 | 0 | 0 | — | — | June 10, 2026 |
| Norden Gregory | Director | 2 | 0 | 0 | — | — | June 10, 2026 |
| YOUNG WILLIAM D | Director | 2 | 0 | 0 | — | — | June 10, 2026 |
What kind of transactions these are 5 Form 4 codes
| Code | Meaning | Rows | Shares | Value at reported prices |
|---|---|---|---|---|
| A | Grant or award | 38 | 126,397 | $103K |
| M | Option exercise or conversion | 28 | 100,660 | $3.5M |
| S | Open-market sale | 28 | 364,240 | $44.3M |
| F | Shares withheld for tax | 13 | 11,566 | $3.3M |
| G | Gift | 3 | 23,521 | — |
What each code means: Form 4 transaction codes.
Members of Congress trading PRAX
Members whose periodic transaction reports name this ticker. Amounts are the sums of the ranges as filed.
| Member | Seat | Trades | Bought | Sold | Range as filed | Latest |
|---|---|---|---|---|---|---|
| Gilbert Ray Cisneros, Jr. | Representative (CA, District 31), Democrat | 2 | 2 | 0 | $2,002–$30K | September 29, 2026 |
Insider transactions
| Filer | Side | Trade date | Disclosed | Lag | Shares | Price | Value | Flags | Source | Share |
|---|---|---|---|---|---|---|---|---|---|---|
| Souza Marcio | Other G | July 8, 2026 | July 8, 2026 | 0d | 2,600 | — | — | indirect | Form 4 ↗ | |
| Souza Marcio | Other G | July 8, 2026 | July 8, 2026 | 0d | 20,521 | — | — | Form 4 ↗ | ||
| DeSimone Jill | Option / conversion M | June 24, 2026 | June 26, 2026 | 2d | 3,034 | — | — | 10b5-1 planderivative | Form 4 ↗ | |
| DeSimone Jill | Option / conversion M | June 24, 2026 | June 26, 2026 | 2d | 8,566 | — | — | 10b5-1 planderivative | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 837 | $316 | $264K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 1,279 | $315 | $403K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 504 | $314 | $158K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 1,004 | $313 | $314K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 2,854 | $312 | $890K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 1,750 | $311 | $544K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 999 | $309 | $309K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 1,240 | $308 | $382K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 683 | $307 | $210K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 320 | $305 | $98K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 120 | $303 | $36K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Sell S | June 24, 2026 | June 26, 2026 | 2d | 10 | $301 | $3,014 | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Option / conversion M | June 24, 2026 | June 26, 2026 | 2d | 3,034 | $147 | $447K | 10b5-1 plan | Form 4 ↗ | |
| DeSimone Jill | Option / conversion M | June 24, 2026 | June 26, 2026 | 2d | 8,566 | $44 | $379K | 10b5-1 plan | Form 4 ↗ | |
| Arbuckle Stuart A | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| Arbuckle Stuart A | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| Chodakewitz Jeffrey | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| Chodakewitz Jeffrey | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| YOUNG WILLIAM D | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| YOUNG WILLIAM D | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| DeSimone Jill | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| DeSimone Jill | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| Cudkowicz Merit Ester | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| Cudkowicz Merit Ester | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| MITCHELL DEAN J | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| MITCHELL DEAN J | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| KINDLER JEFFREY B | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| KINDLER JEFFREY B | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| Norden Gregory | Other A | June 10, 2026 | June 12, 2026 | 2d | 648 | — | — | derivative | Form 4 ↗ | |
| Norden Gregory | Other A | June 10, 2026 | June 12, 2026 | 2d | 1,371 | — | — | Form 4 ↗ | ||
| Mastrocola Lauren | Other A | May 14, 2026 | May 19, 2026 | 5d | 127 | $168 | $21K | late | Form 4 ↗ | |
| Nemiroff Alex | Other A | May 14, 2026 | May 19, 2026 | 5d | 78 | $168 | $13K | late | Form 4 ↗ | |
| Kelly Timothy Edwin | Other A | May 14, 2026 | May 19, 2026 | 5d | 121 | $168 | $20K | late | Form 4 ↗ | |
| Sniecinski Megan | Other A | May 14, 2026 | May 19, 2026 | 5d | 89 | $168 | $15K | late | Form 4 ↗ | |
| Souza Marcio | Other A | May 14, 2026 | May 19, 2026 | 5d | 126 | $168 | $21K | late | Form 4 ↗ | |
| Arbuckle Stuart A | Other A | February 6, 2026 | February 10, 2026 | 4d | 224 | — | — | derivative | Form 4 ↗ | |
| Arbuckle Stuart A | Other A | February 6, 2026 | February 10, 2026 | 4d | 478 | — | — | Form 4 ↗ | ||
| Arbuckle Stuart A | Other A | February 6, 2026 | February 10, 2026 | 4d | 688 | — | — | Form 4 ↗ | ||
| KINDLER JEFFREY B | Other A | February 6, 2026 | February 10, 2026 | 4d | 224 | — | — | derivative | Form 4 ↗ | |
| KINDLER JEFFREY B | Other A | February 6, 2026 | February 10, 2026 | 4d | 478 | — | — | Form 4 ↗ | ||
| KINDLER JEFFREY B | Other A | February 6, 2026 | February 10, 2026 | 4d | 688 | — | — | Form 4 ↗ | ||
| Mastrocola Lauren | Sell F | January 12, 2026 | January 13, 2026 | 1d | 344 | $276 | $95K | Form 4 ↗ | ||
| Sniecinski Megan | Sell F | January 12, 2026 | January 13, 2026 | 1d | 885 | $276 | $244K | Form 4 ↗ | ||
| Nemiroff Alex | Sell F | January 12, 2026 | January 13, 2026 | 1d | 768 | $276 | $212K | Form 4 ↗ | ||
| Kelly Timothy Edwin | Sell F | January 12, 2026 | January 13, 2026 | 1d | 943 | $276 | $260K | Form 4 ↗ | ||
| Mastrocola Lauren | Other A | January 8, 2026 | January 12, 2026 | 4d | 7,500 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Sell F | January 10, 2026 | January 12, 2026 | 2d | 367 | $288 | $106K | Form 4 ↗ | ||
| Mastrocola Lauren | Other A | January 8, 2026 | January 12, 2026 | 4d | 3,750 | — | — | Form 4 ↗ | ||
| Sniecinski Megan | Other A | January 8, 2026 | January 12, 2026 | 4d | 7,700 | — | — | derivative | Form 4 ↗ | |
| Sniecinski Megan | Sell F | January 10, 2026 | January 12, 2026 | 2d | 1,087 | $288 | $314K | Form 4 ↗ | ||
| Sniecinski Megan | Other A | January 8, 2026 | January 12, 2026 | 4d | 9,625 | — | — | Form 4 ↗ | ||
| Nemiroff Alex | Other A | January 8, 2026 | January 12, 2026 | 4d | 5,500 | — | — | derivative | Form 4 ↗ | |
| Nemiroff Alex | Sell F | January 10, 2026 | January 12, 2026 | 2d | 917 | $288 | $265K | Form 4 ↗ | ||
| Nemiroff Alex | Other A | January 8, 2026 | January 12, 2026 | 4d | 6,875 | — | — | Form 4 ↗ | ||
| Kelly Timothy Edwin | Other A | January 8, 2026 | January 12, 2026 | 4d | 7,040 | — | — | derivative | Form 4 ↗ | |
| Kelly Timothy Edwin | Sell F | January 10, 2026 | January 12, 2026 | 2d | 1,335 | $288 | $385K | Form 4 ↗ | ||
| Kelly Timothy Edwin | Other A | January 8, 2026 | January 12, 2026 | 4d | 8,800 | — | — | Form 4 ↗ | ||
| Souza Marcio | Other A | January 8, 2026 | January 12, 2026 | 4d | 22,110 | — | — | derivative | Form 4 ↗ | |
| Souza Marcio | Sell F | January 10, 2026 | January 12, 2026 | 2d | 4,252 | $288 | $1.2M | Form 4 ↗ | ||
| Souza Marcio | Other A | January 8, 2026 | January 12, 2026 | 4d | 27,640 | — | — | Form 4 ↗ | ||
| Mastrocola Lauren | Sell F | January 7, 2026 | January 9, 2026 | 2d | 35 | $293 | $10K | Form 4 ↗ | ||
| Nemiroff Alex | Sell F | January 7, 2026 | January 9, 2026 | 2d | 89 | $293 | $26K | Form 4 ↗ | ||
| Kelly Timothy Edwin | Sell F | January 7, 2026 | January 9, 2026 | 2d | 139 | $293 | $41K | Form 4 ↗ | ||
| Souza Marcio | Sell F | January 7, 2026 | January 9, 2026 | 2d | 405 | $293 | $119K | Form 4 ↗ | ||
| Souza Marcio | Other G | December 30, 2025 | December 31, 2025 | 1d | 400 | — | — | indirect | Form 4 ↗ | |
| Kelly Timothy Edwin | Other A | November 14, 2025 | November 21, 2025 | 7d | 384 | $32 | $12K | late | Form 4 ↗ | |
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 9,100 | — | — | derivative | Form 4 ↗ | |
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 5,652 | — | — | derivative | Form 4 ↗ | |
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 2,434 | — | — | derivative | Form 4 ↗ | |
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 6,230 | — | — | derivative | Form 4 ↗ | |
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 1,714 | — | — | derivative | Form 4 ↗ | |
| Nemiroff Alex | Sell S | November 20, 2025 | November 21, 2025 | 1d | 9,100 | $194 | $1.8M | Form 4 ↗ | ||
| Nemiroff Alex | Sell S | November 20, 2025 | November 21, 2025 | 1d | 977 | $193 | $189K | Form 4 ↗ | ||
| Nemiroff Alex | Sell S | November 20, 2025 | November 21, 2025 | 1d | 13,339 | $193 | $2.6M | Form 4 ↗ | ||
| Nemiroff Alex | Sell S | November 20, 2025 | November 21, 2025 | 1d | 1,714 | $191 | $327K | Form 4 ↗ | ||
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 9,100 | $57 | $518K | Form 4 ↗ | ||
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 5,652 | $44 | $251K | Form 4 ↗ | ||
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 2,434 | $44 | $108K | Form 4 ↗ | ||
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 6,230 | $134 | $833K | Form 4 ↗ | ||
| Nemiroff Alex | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 1,714 | $84 | $144K | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 5,250 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 2,351 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 207 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 2,680 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 1,557 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 508 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 1,047 | — | — | derivative | Form 4 ↗ | |
| Mastrocola Lauren | Sell S | November 20, 2025 | November 21, 2025 | 1d | 2,145 | $193 | $413K | Form 4 ↗ | ||
| Mastrocola Lauren | Sell S | November 20, 2025 | November 21, 2025 | 1d | 11,455 | $192 | $2.2M | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 5,250 | $57 | $299K | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 2,351 | $44 | $104K | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 207 | $44 | $9,191 | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 2,680 | $43 | $116K | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 1,557 | $134 | $208K | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 508 | $84 | $43K | Form 4 ↗ | ||
| Mastrocola Lauren | Option / conversion M | November 20, 2025 | November 21, 2025 | 1d | 1,047 | $50 | $52K | Form 4 ↗ | ||
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 19,198 | $140 | $2.7M | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 308 | $132 | $41K | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 487 | $132 | $64K | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 1,661 | $130 | $216K | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 250,000 | $104 | $26.1M | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 27,287 | $101 | $2.8M | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 559 | $100 | $56K | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 1,363 | $92 | $125K | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 447 | $91 | $41K | indirect | Form 4 ↗ | |
| Adage Capital Management, L.P. | Sell S | October 16, 2025 | October 17, 2025 | 1d | 12,600 | $90 | $1.1M | indirect | Form 4 ↗ |
Congressional trades
| Filer | Side | Trade date | Disclosed | Lag | Shares | Price | Value | Flags | Source | Share |
|---|---|---|---|---|---|---|---|---|---|---|
| Gilbert Ray Cisneros, Jr. | Buy | September 29, 2026 | October 12, 2026 | 13d | — | — | $1,001–$15K | House PTR ↗ | ||
| Gilbert Ray Cisneros, Jr. | Buy | July 30, 2026 | September 4, 2026 | 36d | — | — | $1,001–$15K | House PTR ↗ |
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Guides for this page
- What is SEC Form 4? Who files: officers, directors and owners of more than 10% of a class of the company's shares.
- Form 4 transaction codes P = purchase. S = sale. These are the two market trades.
- Insider buying vs insider selling Selling outweighs buying by a wide margin in normal times.
- How to read a congressional trade report Owner tells you whose asset it was: the member, the spouse, a dependent child, or held jointly.
- Why congressional trade amounts are ranges There are ten ranges; the lowest is $1,001–$15,000 and the highest is over $50,000,000.
Sources and method
| Source | Filings | Rows | First filed | Newest filed | Read the originals |
|---|---|---|---|---|---|
| House Clerk, periodic transaction reports | 2 | 2 | September 4, 2026 | October 12, 2026 | House Clerk search |
| SEC EDGAR, Form 4 | 35 | 110 | October 17, 2025 | July 8, 2026 | Form 4 list on EDGAR |
Site built October 22, 2026. Every row in the tables above links to its own filing. To quote a figure, use the Cite button at the top of the page; see how to cite and reuse.
Insider rows are Form 4 filings for this issuer from SEC EDGAR; congressional rows are periodic transaction reports parsed from the House Clerk and the Senate eFD. Values use the reported price for Form 4 and the disclosed range for Congress. See methodology and corrections.
Not investment advice. Disclosures are shown as filed and may lag the trade or be amended. No recommendation is made or implied.